Like a number of European capitals, Berlin offers a series of areas with points of interest, rather than a single specific centre, so the reliable S Bahn trains are likely to come in useful.
A great place to start is on Unter den Linden, situated just east of the Brandenburg Gate. Some of the Berlin's most treasured artistic and architectural sites can be found at one end on Museumsinsel. Shopaholics should look no further than the famous Kurfurstendamm, with its numerous designer boutiques and hidden passages. However, both Unter den Linden and Friedrichstrasse continue their ascent to prominence and should not be missed. Take a visit to newly revived Potsdamer Platz, and don't miss the most famous sites such as the Berlin Wall or the beautiful Reichstag building; home to the German Parliament.